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#An open discussion. Welcome constructive suggestions or questions over this topic. #IVD #dna Sample collection device used for collecting and preserving sample from exfoliated buccal cells is usually in a form of kit with tube(s) of liquid buffers/reagents. The most wellknown application of such collection device is the sample collection tools in 23andMe kits. The volum of 2ml saliva sample is good enough for carrying out DNA extraction/purification, and subsequent genetic testing and analyzing. Well the fact is buccal swaps can serve the same function as the tool of collecting saliva but more user -friendly. Sample DNA kept on swaps can fully meet the criteria of DNA testing for ancestry and health risks. Besides, buccal swaps are more convenient and safe carried during transporation. The key problem is around "how to well preserve the sample, and avoid DNA degradation". FineGene's R&D department has been developing a samll integrated device without any liquid buffers, but still preventing sample DNA from being rapid degradated. In order to retain DNA in good condition, buccal swaps in the device are designed to collect DNA from exfoliated buccal cells, and then safekept in a special mini container coated with reagent-prepared fibers. It has been tested and then demostrates a stable performance of high DNA yield. Although its mechanism is somewhat similar to FTA card, it provides a concise structure, simple operations and good preservation of sample DNA. We have some concerns before the new product is going to be launched. Firstly, during the testing stage in lab, though the sample DNA can be well preserved over months, can it be a key advantage to attract clients' attention? Secondly, if its cost is much lower than saliva collection kit, in the industry, will it be widely used? And what else we should think over? |
